Dry Eye Definition

Dry eye is a multifactorial disease of the ocular surface characterized by a loss
of homeostasis of the tear film, and accompanied by ocular symptoms,
in which tear film instability and hyperosmolarity, ocular surface inflammation
and damage, and neurosensory abnormalities play etiological roles.




Prevalence of Dry Eye Disease

  • The Prevalence of Dry eye Disease increases significantly with age.
  • Around the world, between 5% and 34% of people suffer from dry eye.

 

Distribution of Dry Eye by Type
According to data from a cohort of 224 patients with dry eye disease published in 2012

 

Aqueous-deficient
Lacrimal glands fail to produce enough watery tear component

Lipid-deficient Dry Eye
Also known as meibomian gland dysfunction (MGD), the lipid layer of the tear film is depleted, causing evaporation and instability of the tear film.

Mixed or Unknown
Approximately half of all patients have both lipid-and aqueous-deficient dry eye or clinical signs of unknown origin.